The Global Lungs Initiative (GLI) equations are the first global multi-ethnic reference equations for spirometry that span all-ages. These are the result of unprecedented, unselfish and professional international cooperation endorsed by five international societies. Briefly, data from 74,187 healthy non-smokers (57.1% females) aged 3-95 years were used to derive multi-ethnic reference equations using modern statistical methods, including development of age dependent lower limits of normal.

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